In the previous paper of this series, risks associated with potential hydrogen vapor cloud explosions were discussed, which is perhaps the most recognizable type of hydrogen hazard. However, hydrogen is stored and transported in high-pressure vessels and pipes, which represents additional inherent hazards. This paper focuses on hazards associated with hydrogen in high-pressure applications. The sudden release of high-pressure hydrogen gas represents several potential hazards and risks. An accidental failure could result in injuries to personnel nearby if fragments or projectiles are thrown from the failed vessel or pipe. The sudden release of high-pressure hydrogen gas could also cause a blast wave that could injure personnel. Secondary debris impacted by projectiles or blast waves can result in injuries as well. In addition, an accidental release of high-pressure hydrogen gas can result in damage to infrastructure and equipment in the vicinity.